| Immunogen | Bovinebrainmicrotubuleprotein. | 
| Clone | AP20 | 
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. | 
| Host | Mouse | 
| Specificity | MAB3418bindsspecificallytoMAP-2. | 
| Isotype | IgG | 
| SpeciesReactivity | BovineChickenHumanMouseRatXenopusQuail
 | 
| SpeciesReactivityNote | Ratandmouse.Expectedtocross-reactwithhuman,cow,chicken,quail,andXenopus. | 
| AntibodyType | MonoclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Thisgeneencodesaproteinthatbelongstothemicrotubule-associatedproteinfamily.Theproteinsofthisfamilyarethoughttobeinvolvedinmicrotubuleassembly,whichisanessentialstepinneurogenesis.Theproductsofsimilargenesinratandmouseareneuron-specificcytoskeletalproteinsthatareenrichedindentrites,implicatingaroleindeterminingandstABIlizingdentriticshapeduringneurondevelopment.Anumberofalternativelysplicedvariantsencodingdistinctisformshavebeendescribed. | 
| GeneSymbol | MAP2MAP2BMAP-2MAP2CDKFZp686I2148MAP2A
 | 
| PurificationMethod | ProteinAPurfied | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P11137#TheexactfunctionofMAP2isunknownbutMAPsmaystabilizethemicrotubulesagainstdepolymerization.Theyalsoseemtohaveastiffeningeffectonmicrotubules. SIZE:1827aminoacids;199539Da
 PTM:MAP2A/cisphosphorylated.PhosphorylateduponDNAdamage,probablybyATMorATR.
 SIMILARITY:SwissProt:P11137##Contains3Tau/MAPrepeats.
 | 
| MolecularWeight | 230kDa |