| Immunogen | Crudesynapticimmunoprecipitate(Human). | 
| Clone | SP10 | 
| Host | Mouse | 
| Specificity | Synaptobrevin[VAMP].MAB333reactswithVAMP-1andVAMP-2fusionproteinexpressedinbacterialsystem. | 
| Isotype | IgM | 
| SpeciesReactivity | - Human
 - Hamster
 - Pig
 - Rat
 - Salamander
 
  | 
| AntibodyType | MonoclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Synaptobrevins/VAMPs,syntaxins,andthe25-kDsynaptosomal-associatedproteinSNAP25arethemaincomponentsofaproteincomplexinvolvedinthedockingand/orfusionofsynapticvesicleswiththepresynapticmembrane.VAMP1isamemberofthevesicle-associatedmembraneprotein(VAMP)/synaptobrevinfamily.Multiplealternativesplicevariantsthatencodeproteinswithalternativecarboxyendshavebeendescribed,butthefull-lengthnatureofsomevariantshasnotbeendefined. | 
| GeneSymbol | - VAMP1
 - SYB1
 - Synaptobrevin-1
 - VAMP-1
 - DKFZp686H12131
 
  | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P23763#Involvedinthetargetingand/orfusionoftransportvesiclestotheirtargetmembrane. SIZE:118aminoacids;12902Da SUBUNIT:InteractswithVAPAandVAPB. SUBCELLULARLOCATION:Isoform1:Cytoplasmicvesicle,secretoryvesicle,synapticvesiclemembrane;Single-passtypeIVmembraneprotein(Bysimilarity).&Isoform2:Cytoplasmicvesiclemembrane;Single-passtypeIVmembraneprotein(Bysimilarity).&Isoform3:Mitochondrionoutermembrane;Single-passtypeIVmembraneprotein. TISSUESPECIFICITY:Nervoussystem,skeletalmuscleandADIposetissue. SIMILARITY:SwissProt:P23763##Belongstothesynaptobrevinfamily.&Contains1v-SNAREcoiled-coilhomologydomain. |