| Immunogen | Electrophoreticallypuretrp-E-peripherinfusionprotein[Dev.BrainRes.(1990)57:235-248],containingallbutthe4Nterminalaminoacidsofratperipherin.FusionproteinpurifiedfrombacterialinclusionbodiesbyDEAE-cellulosechromatographyin6MureafollowedbypreparativeSDS-PAGE. | 
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. | 
| Host | Rabbit | 
| Specificity | RecognizesPeripherin.Theantibodystainsa~57kDabandcleanlyandspecificallyanddoesnotstainvimentin,GFAP,alpha-internexinoranyoftheneurofilamentsubunits.Strongstainingonrat,mouse,human,pigandcowperipherin.Doesnotstainchicken,quailorothermoredistantlyrelatedspecieswhichappeartolackperipherin. | 
| SpeciesReactivity |  | 
| SpeciesReactivityNote | Strongstainingonratandhuman.Cross-reactswithmouse,pig,andbovine.Otherspeciesnottested. | 
| AntibodyType | PolyclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Thisgeneencodesacytoskeletalproteinfoundinneuronsoftheperipheralnervoussystem.TheencodedproteinisatypeIIIintermediatefilamentproteinwithhomologytoothercytoskeletalproteinssuchasdesmin,andisadifferentproteinthattheperipherinfoundinphotoreceptors.Mutationsinthisgenehavebeenassociatedwithsusceptibilitytoamyotrophiclateralsclerosis. | 
| GeneSymbol | PRPHPeripherinPRPH1peripherinNEF4
 | 
| PurificationMethod | Unpurified | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P41219#Class-IIIneuronalintermediatefilamentprotein. SIZE:470aminoacids;53651Da
 SIMILARITY:SwissProt:P41219##Belongstotheintermediatefilamentfamily.
 | 
| MolecularWeight | 56-58kDa |